I don’t think AxQuery objects have an openLink method, where did you find that? I don’t think that’s correct.
Anyway, you don’t need AxQuery, good old jQuery will do just fine:
$('iframe').attr('src','http://www.axure.com')
That assumes you only have one iframe. If you have multiple and have named it, use this instead:
$('[data-label=name] iframe').attr('src','http://www.axure.com')