Open page in inline frame from a command in a different inline frame

Is it possible to open a page in inline frame using a command (e.g. OnClick event) from a widget in a different inline frame?

See attached. Page 2 is loaded into Page 1’s first inline frame and contains a button. When the button is clicked, the desired behavior is for Page 3 to load into Page 1’s second inline frame.

Thanks in advance.